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Predicting the Onset of Alzheimer Disease Symptoms

Previous studies of in vitro and in vivo aggregation of β-amyloid have suggested that there is a tipping point above which aggregates become nuclei for further aggregation, which proceeds at a constant and predictable rate after the tipping point.

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Psilocybin May Not Be More Efficacious Than a Common Antidepressant

The first-line treatment for major depressive disorder is a selective serotonin reuptake inhibitor, but not all patients respond to this treatment. Psilocybin, a psychedelic made by certain mushrooms, is one alternative that is receiving renewed interest.

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Migraine

FDA Approves Atogepant for Prevention of Episodic Migraines

Clopidogrel for Prevention of New-Onset Migraines After Transcatheter Atrial Septal Defect Closure

Eptinezumab Infusion During a Migraine Attack Provides Rapid Relief of Migraine Pain and Symptoms

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Depression

Nonresponders to Esketamine Nasal Spray plus Oral Antidepressants May Still Respond by 4 Weeks of Treatment

Addition of Online Cognitive Behavioral Therapy Workshops to Usual Care May Improve Symptoms of Postpartum Depression

Risk of Relapse After Discontinuation versus Maintenance of Antidepressant Therapy

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