Prescription opioid abuse is a significant public health concern in the United States, particularly abuse of controlled-release formulations that contain higher opioid content.
A prescription opioid addiction and abuse epidemic has been escalating in the United States over the past 2 decades, having progressively developed into a pressing national public health concern.
Since the early 1970s, the United States has declared a war on drugs, focusing on ways in which to reduce the use and abuse of illicit and addicting drugs.
The human toll from opioid-related abuse and misuse in the United States is a serious public health problem that must be addressed on all fronts.

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